They are non abrasive (to avoid worsening any tooth wear related sensitivity). This means an RDA of 250 or below. Akin M, Basciftci FA. Can white spot lesions be treated effectively? Angle Orthod. 2012;82(5):770–5. Regular disturbance of the plaque biofilm by brushing twice a day with a fluoride toothpaste [ 7]. Other fluoride agents may also be added if the caries risk warrants their use [ 8– 11]. RECALDENT ® or Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) is a unique ingredient derived from naturally occurring protein found in cow’s milk. RECALDENT ® is exported worldwide and used as ingredient in various functional foods and dental products. The CPP-ACP technology is the result of many years of research at the University of Melbourne into the anticariogenic properties of milk. There is a high-level of evidence supporting the ability of CPP-ACP to remineralise early caries lesions and prevent their progression [ 10, 11, 12, 13, 14]. There are now twelve published systematic meta-analyses of these clinical studies to support the use of CPP-ACP to lower caries risk [ 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22]. In addition, CPP-ACP effectiveness has also been demonstrated in relation to the reduction of cariogenic bacteria and increased colonization of commensal microorganisms, and the reduction of dentine hypersensitivity [ 23, 24, 25, 26].

Plonka KA, Pukallus ML, Holcombe TF, Barnett AG, Walsh LJ, Seow WK. Randomized controlled trial: a randomized controlled clinical trial comparing a remineralizing paste with an antibacterial gel to prevent early childhood caries. Pediatr Dent. 2013;35(1):8–12.Azarpazhooh A, Main PA. Pit and fissure sealants in the prevention of dental caries in children and adolescents: a systematic review. Journal. 2008;74(2):171–7. Lechuga VM. Exploring culture from a distance: the utility of telephone interviews in qualitative research. Int J Qual Stud Educ. 2012;25(3):251–68. Matsumoto-Nakano M. Role of Streptococcus mutans surface proteins for biofilm formation. Jpn Dent Sci Rev. 2018;54:22–9.

During this process of change, participants identified key facilitators for changing daily routines to include TMP application. These included: (a) seeing the long-term positive effects of TMP, (b) seeing research evidence, (c) TMP being endorsed by their dentist, (d) being educated by the dentist/dental team on how to apply the product and (e) having the support of a family member. Beerens MW, van der Veen MH, van Beek H, ten Cate JM. Effects of casein phosphopeptide amorphous calcium fluoride phosphate paste on white spot lesions and dental plaque after orthodontic treatment: a 3-month follow-up. Eur J Oral Sci. 2010;118(6):610–7. Zheng H, Thomas PA. Marital status, self-rated health, and mortality: overestimation of health or diminishing protection of marriage? J Health Soc Behav. 2013;54(1):128–43. Dental treatment: Tooth whitening can cause temporary sensitivity. Professional cleaning and fillings can also lead to sensitivity.The Deep Clean variety is a gel as opposed to a paste, and additional ingredients compared to the original flavour include Pentasodium Triphosphate and SLS! It would be so much easier if you could buy it at a chemist (ID12, female, 55–64 years old, Sjogren's syndrome). Lemos JA, Palmer SR, Zeng L, Wen ZT, Kajfasz JK, Freires IA, Abranches J, Brady LJ. The biology of Streptococcus mutans. Microbiol Spectr. 2019;7(10):1128. AIHW. Oral health behaviours in the Australian population 2004–06. Canberra: Australian Institute of Health Welfare; 2009. Bader JD. Casein phosphopeptide-amorphous calcium phosphate shows promise for preventing caries. Evid Based Dent. 2010;11(1):11–2.

If you are getting a lot of sensitivity from one tooth I would recommend you see a dental professional who can exclude any problems with the tooth. They might also be able to offer treatments, depending on the cause of the sensitivity, such as applying a professional varnish, or repairing the tooth with filling material. Any advice I give is without assessing you and doesn’t replace advice given by your own dentist.One might also consider it somewhat unusual that the bulk of the evidence on remineralisation studies comes from orthodontic patients who are a very select group of individuals undergoing specialist dental care and not typical of the general population. However it would be unwise to dismiss the results because of the narrow specificity of the target group as it would reduce the data set to two studies. If one considers the orthodontic publications there is a some degree of evidence for the benefits of regression of white spot lesions, with four studies [ 33, 37, 38, 40] showing positive results and three [ 35, 36, 41] showing no significant difference to the control groups. When the three studies [ 35, 39, 41] utilising Tooth Mouth Plus® (MI Paste Plus®) are considered – Krithikadatta et al. [ 39] was the only one with a direct comparison between Tooth Mousse® and Tooth Mousse Plus®. The results of this study did not show a significant difference between the non-fluoride and fluoride-containing forms of the CPP-ACP crème and the authors suggested that further studies would be required to confirm these results. Since CPP is a tryptic digest of the milk protein casein and is composed of peptides and phosphate groups, it is likely that CPP might be a nutrient for S. mutans. To study this possibility, the bacteria were exposed to increasing concentrations of CPP, and the planktonic growth and ATP content were analyzed after 6 and 24 h (Additional file 1: Fig. S1). We observed that CPP treatment did not lead to an increased bacterial growth after 6 h, but caused a significant increase in the ATP content at doses of 5–50 mg/ml (Additional file 1: Fig. S1A). After 24 h incubation, there was 1.5-time more bacteria in samples treated with 10–50 mg/ml CPP than in control samples (Additional file 1: Fig. S1B). Again, we observed that CPP increases the ATP content per bacterium at concentrations 10–50 mg/ml when compared to control bacteria (Additional file 1: Fig. S1B). Thus, CPP may contribute to the increase in ATP content in bacteria exposed to GC and GCP tooth mousse, but it is likely that other components of the tooth mousse contribute to the increased proliferation of S. mutans. Both GC and GCP exerted strong anti-biofilm effects on S. mutans The interview was divided into opening questions, transitional questions and concluding questions (Table 3). Interviews included open-ended opening questions about oral health (When I say oral health, what is the first thing that comes to your mind? How important to you is your oral health and why?). Then, transitional questions were asked about the experience of oral health before and after using TMP (Tell me about your experience of using GC Tooth Mousse Plus. Why were you prescribed this product? What difference did this product make to your oral health?). Participants were invited to talk specifically about their own experience in applying the product, their perceptions, and expectations about the product efficacy and what changes they have observed in their oral health status after starting to use the product. In brief, the interviewer (AS) explored how participants introduced TMP into daily routines, what were their experiences of oral health before, during and after using TMP, and how this process was influenced by their social context.

Mei L, Chieng J, Wong C, Benic G, Farella M. Factors affecting dental biofilm in patients wearing fixed orthodontic appliances. Prog Orthod. 2017;18:4. While the focus of this study was not on the relationship between dental professionals and patients, it was evident that the quality of such relationship was essential for participants being encouraged to modify their daily routines. Participants talked about the value of TMP being prescribed by a dentist, and at the same time, being educated by dentists and members of a dental team on how to apply the product. It is well established in the literature that dentists’ and dental team members’ attitude towards patients can impact on treatment acceptance and home care compliance [ 9, 39, 40, 41, 42]. Our findings confirm that having a positive relationship between dental professionals and patients can be a facilitator of change.Ultimately, tooth sensitivity is caused by exposed dentin tubules (the nerves that sense pain lie within these parts of the tooth). A change in hot/cold/pH etc causes movement of the nerve within the tubule, which causes a pain signal to be sent to your brain.